Cat #: 55-8043XB
Caprico Biotechnologies 1120195 CD4 iFluor™700 Antibody, Clone SK3, Mouse IgG1,k, 100 Tests/Unit







Cat #: 55-8043XB
Caprico Biotechnologies 1120195 CD4 iFluor™700 Antibody, Clone SK3, Mouse IgG1,k, 100 Tests/Unit
Clone SK3, Mouse IgG1,k
100 Tests/Unit
Brand: Caprico Biotechnologies- This mouse monoclonal antibody selectively binds with a 55-59kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily
- Utilizes iFluor™ fluorescent labeling optimized for extremely strong fluorescence
- Highly specific and little to no cross reactivity to ensure accurate, reproducible results in Flow Cytometry
- >90% pure tested via polyacrylamide gel electrophoresis (PAGE)
- More conjugations and unit sizes available. Contact us at support@geneseesci.com to inquire.

$312.60
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Clone SK3, Mouse IgG1,k
100 Tests/Unit
Brand: Caprico Biotechnologies- This mouse monoclonal antibody selectively binds with a 55-59kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily
- Utilizes iFluor™ fluorescent labeling optimized for extremely strong fluorescence
- Highly specific and little to no cross reactivity to ensure accurate, reproducible results in Flow Cytometry
- >90% pure tested via polyacrylamide gel electrophoresis (PAGE)
- More conjugations and unit sizes available. Contact us at support@geneseesci.com to inquire.
The clone SK3, a mouse monoclonal antibody selectively binds with a 55-59kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. CD4 contains four extracellular Ig-like domains (D1-D4). The epitope for SK3 is located within the D3 domain of the protein, which has a structure resembling an Ig variable domain. Expression of CD4 is observed in subsets of T lymphocytes, monocytes, macrophages, and dendritic cells. Through interaction of MHC-II, CD4 facilitates cell-cell interaction, thymic differentiation, and activation of downstream signaling cascades. HIV infection of T-cells is instigated through binding of HIV to CD4. Binding of SK3 antibody blocks HIV infection through CD4 and also blocks the mixed lymphocyte reaction (MLR).
iFluor™ fluorophores are optimized for strong fluorescence, high photostability and pH independence on proteins. They are avaialble to span the full UV-visible-IR spectrum. iFluor™700 is a great alternative to Alexa Fluor® 700. Do you need an antibody for an antigen you don't see on our website? Do you need a different conjugation than what we have listed? We have a wide selection of antigens with a variety of conjugations available. Please reach out to us at support@geneseesci.com.
Conjugation | iFluor™700 |
---|---|
Excitation Laser | Red (633nm) |
Reactivity | Human |
Host | Mouse |
Antigen | CD4 |
Clone | SK3 |
Isotype | IgG1,k |
Status | RUO |
Size | 100 Tests/Unit |
Storage | 2-8°C and protected from prolonged exposure to light |
Formulation | PBS, pH7.2, 0.09% NaN3 and 0.2% (w/v) BSA |
Immunogen | Human peripheral blood T cells |
Clonality | Monoclonal |
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