Vivapure®Maxi Ion Exchange spin columns are centrifugal devices, based on Sartobind Membrane Adsorber technology as their chromatography matrix. The devices are ready-to-use and cannot run dry by their design. For many protein purification applications, they can replace time-consuming column chromatography. The rapid 1-2-3 bind-wash-elute protocol especially lends itself to screening applications, where many samples are processed parallel. Vivapure®Maxi is available with three different membrane chemistries and with medium (15-20 mg/unit) or high (60-80 mg/unit) protein binding capacity. Vivapure®Maxi units are intended for use in swing-out rotors and accommodate 20 ml and 19 ml samples, respectively. They can also be run in fixed-angle rotors with reduced sample volume of 10.5 ml.